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Immunity and infection

Hepatitis B immunity test (surface antibody, quantitative)

Written by the Zenlo Health editorial teamUpdated 2026-10-14Education onlyHow we review
Short answerThe hepatitis B immunity test measures surface antibody (anti-HBs) in your blood. The CDC considers 10 mIU/mL or higher a protective level after vaccination. Health care workers, students, and people with a partner who has hepatitis B often need this titer.
Fasting and prep
No fasting needed. Follow the instructions on your lab order.
Turnaround
Usually 1 to 3 days.
Also called
anti-hbs, hbsab, hepatitis b surface antibody, hep b titer, hepatitis b titer

What it measures

Your body makes anti-HBs after the hepatitis B vaccine or after recovering from infection. Levels often fall over the years after vaccination, yet most people who once reached 10 mIU/mL stay protected because their immune memory remains. A core antibody (anti-HBc) test tells vaccine immunity apart from past infection.

Who should consider it

  • Health care workers and students, 1 to 2 months after finishing the vaccine series
  • Partners and household members of someone with hepatitis B
  • People on dialysis or with weakened immune systems
  • Babies born to parents with hepatitis B, at the time their pediatrician advises
  • Adults unsure whether they were vaccinated

How to read your result

Hepatitis B surface antibody (mIU/mL)

The CDC uses 10 mIU/mL or higher as the protective level. Values can run far above 100. Lab ranges and units differ, so use the cutoff printed on your report.

  • 10 mIU/mL or higher means you are considered immune, per CDC.
  • Below 10 after a full vaccine series may mean you did not respond, or that levels faded with time. A clinician may suggest a booster dose and a repeat test.
  • A positive anti-HBs alone does not show whether immunity came from the vaccine or past infection. The core antibody test answers that.
  • This test does not check for current infection. The surface antigen (HBsAg) test does.

Reference ranges differ between labs. Use the range printed on your own report.

What to do next

If your level is below 10 mIU/mL and you have no record of vaccination, talk with a clinician about the vaccine series. If you finished a series long ago, many clinicians give one booster and recheck. Health care workers should follow CDC and employer protocols, which spell out testing after each step.

Where to order Hepatitis B immunity test

These sellers include an independent physician order. You pay online and visit a partner lab. Availability, price, and lab network vary, so confirm at checkout.

Private MD Labs

Online lab seller
Quest or LabcorpPay per testPay after results
Order
Every order reviewed by a physician. Says you pay $1 to start and the rest after results.
Results
Secure online portal with plain-English explanations. Says many results arrive overnight.

HealthLabs

Online lab seller
Quest or LabcorpPay per test
Order
Online or by phone. No doctor referral or insurance needed.
Results
Secure HealthLabs account. Says 1 to 3 business days.

Walk-In Lab

Online lab seller
Lab not namedPay per test
Order
Online, no insurance or doctor order needed. Shows a $6 physician fee per order on popular tests.
Results
Online account. Turnaround not stated on its homepage.

Quest Health

Lab-run
QuestPay per testAt-home optionResults in lab account
Order
Buy online and book a Quest appointment. An independent provider is involved.
Results
Online as soon as ready, with an email alert. Provider discussion included at no extra cost.

Seller details come from each seller's own site and can change. Confirm price, lab location, and state availability at checkout.

Ordering several tests? Plan them together · Filter all sellers

Questions people ask

What hepatitis B titer level means I am immune?

The CDC uses 10 mIU/mL or higher as protective. Some labs report only positive or negative, so a quantitative test shows the actual number.

My titer is low years after vaccination. Am I unprotected?

Not necessarily. Most people who responded to the vaccine keep immune memory even after antibody levels fade. A clinician can give a booster and recheck if your job requires proof.

Does a positive surface antibody mean I had hepatitis B?

It can come from the vaccine or past infection. A core antibody test shows which.

Can I order a hepatitis B titer without a doctor?

Yes. Online sellers include a physician order and a blood draw. Look for a quantitative test if your school or employer needs a number.

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